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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANK3 All Species: 10.91
Human Site: T2137 Identified Species: 40
UniProt: Q12955 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12955 NP_001140.2 4377 480410 T2137 F E T R S E K T P S A P Q S A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001095243 3920 430252 E1758 P I R V K G K E D V P K K T T
Dog Lupus familis XP_536358 4380 479893 T2137 F E T R S E K T P S A P Q S A
Cat Felis silvestris
Mouse Mus musculus Q8C8R3 3898 426243 V1737 I G S I K D K V K A L Q K R V
Rat Rattus norvegicus NP_001029156 2622 284424 M461 V N I V S Q L M H H G A S P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421546 4320 474071 T2137 F E T R S E K T P S A P Q S A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001921230 4028 442548 S1866 L K S A T S S S P L S N S Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 36.5 94.5 N.A. 36.1 55.9 N.A. N.A. 81.8 N.A. 58.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 51.9 96.8 N.A. 51.7 57.7 N.A. N.A. 88.9 N.A. 71.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 6.6 100 N.A. 6.6 6.6 N.A. N.A. 100 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 20 100 N.A. 33.3 13.3 N.A. N.A. 100 N.A. 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 15 0 0 0 0 0 15 43 15 0 0 43 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 15 0 0 15 0 0 0 0 0 0 % D
% Glu: 0 43 0 0 0 43 0 15 0 0 0 0 0 0 15 % E
% Phe: 43 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 15 0 0 0 15 0 0 0 0 15 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 15 15 0 0 0 0 0 % H
% Ile: 15 15 15 15 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 15 0 0 29 0 72 0 15 0 0 15 29 0 0 % K
% Leu: 15 0 0 0 0 0 15 0 0 15 15 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % M
% Asn: 0 15 0 0 0 0 0 0 0 0 0 15 0 0 15 % N
% Pro: 15 0 0 0 0 0 0 0 58 0 15 43 0 15 0 % P
% Gln: 0 0 0 0 0 15 0 0 0 0 0 15 43 15 0 % Q
% Arg: 0 0 15 43 0 0 0 0 0 0 0 0 0 15 0 % R
% Ser: 0 0 29 0 58 15 15 15 0 43 15 0 29 43 0 % S
% Thr: 0 0 43 0 15 0 0 43 0 0 0 0 0 15 15 % T
% Val: 15 0 0 29 0 0 0 15 0 15 0 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _